Susceptibility-based analysis of dynamic gadolinium bolus perfusion MRI
نویسندگان
چکیده
منابع مشابه
Dynamic susceptibility MRI with a pre-bolus administration design for improved absolute quantification of perfusion
Purpose Reproducible absolute quantification of cerebral blood volume (CBV) and cerebral blood flow (CBF) by dynamic susceptibility contrast MRI (DSC-MRI) is difficult to achieve, for example, due to partial-volume effects (PVEs). Rescaling of the arterial input function (AIF) using a corrected venous output function (VOF) in DSC-MRI has been shown to improve the correlation between CBF estimat...
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List of Papers This thesis is based on the following papers, which are referred to in the text by their Roman numerals. Abbreviations ADC Apparent diffusion coefficient AIF Arterial input function ASL Arterial spin labeling CBF Cerebral blood flow CBV Cerebral blood volume CPB Cardio pulmonary bypass DSC-MRI Dynamic susceptibility contrast MRI MRI Magnetic resonance imaging MRS Magnetic resonan...
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Since the first studies in the late 1980s and early 1990s, dynamic susceptibility contrast MRI (DSC-MRI, also known as ‘bolus tracking’) has become a very powerful technique for the assessment of perfusion, and perfusion-related parameters (see (1,2) for recent reviews). Despite the need of an exogenous MR agent (cf. arterial spin labeling techniques), DSC-MRI is currently the most common MR pe...
متن کاملQuantification Issues in Bolus-Tracking Perfusion MRI
Bolus-tracking perfusion MRI is based on the monitoring of the first passage of a bolus of contrast agent through the brain tissue and a brain-feeding artery. The contrast agent is injected rapidly in the antecubital vein in the patients arm by means of an MR-compatible power injector. This bolus of contrast agent is pushed in the direction of the heart by means of a saline flush. Continuous dy...
متن کاملComparison of methods for quantitative analysis of dynamic susceptibility contrast enhanced brain perfusion MRI
Quantitative cerebral blood flow (CBF) can be obtained from dynamic susceptibility contrast (DSC) MRI using for instance the truncated singular value decomposition (tSVD). Block-circulant SVD and reformulated SVD (rSVD) are modified SVD approaches. The purpose of this study is to compare the different approaches. The optimal truncation thresholds (PSVD) for tSVD and block-circulant SVD are dete...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2014
ISSN: 0740-3194
DOI: 10.1002/mrm.25144